Mesothelioma - Thoracic Imaging

Title: Thoracic Imaging - Mesothelioma
Diagnosis: Mesothelioma
Author: Martins Martina
Comment: Howarth Nigel
Hospital: HUG
Department: Département de Radiologie
State: Terminée
Date: 21.03.2003
: 3395
KeyWords: Mesothelioma; pleura
Anatomy: Thorax; pleura
Chapter: Pleura
ACR: 6.3254

Clinical Presentation: Left chest pain with fatigue and weightloss.
Comment: Mesothelioma is a primary cancer of the pleura orperitoneum. The
latent period between the first exposure toasbestos and the development of the tumour is
approximately 30 to40 years. The threshold dose is unknown, and mesotheliomas
havebeen known to occur after only a few months of exposure toasbestos. A focal,
nodular, irregular thickening of the pleura issuggestive of a mesothelioma. Varying degrees
of pleural effusioncan also be seen.
Description: The chest X-ray shows nodular thickening of theparietal and
mediastinal pleura, associated with volume loss of theleft hemithorax. CT images confirm
the presence of irregularnodular thickening of the pleural with pericardialinvolvement.

Order: 0
Dislocation: 0
Polytrauma: 0
Open: 0
Pathologic: 0
Operation: 00.00.00
Graft: 0

References: Marom EM, Erasmus JJ, Pass HI, Patz EF Jr. The role ofimaging in
malignant pleural mesothelioma. Semin Oncol.2002;29:26-35. Boutin C, Schiesser M,
Frenay C, Astoul Ph.Malignant pleural mesothelioma. Eur Respir J.
1998;12:972-81.Antman KH. Natural history and epidemiology of malignantmesothelioma.
Chest. 1993;103:373S. Miller WT Jr, Gefter WB, MillerWT Sr. Asbestos-related chest
diseases: Plain radiographicfindings. Semin Roentgenol. 1992;27:102.

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